Confused by what you’ve read about weight loss medication? You’re not alone. Every day, new claims about Mounjaro, Wegovy and other GLP-1 injections spread across forums, social media, and even in conversations between patients. Some are accurate, but many are myths, half-truths, or taken out of context.
At Weight Loss Fact Checker, we collect the most common questions patients are asking — about side effects, symptoms, results, and safety — and we put them under the microscope. Each claim is labelled as Fact or Fiction with a clear, evidence-based explanation.
This section is the main hub of our website and is updated regularly.
You’ll find answers to real patient concerns.
Every answer is backed by scientific research, clinical guidance, and medical expertise, so you can be confident you’re reading facts — not hype.

Fact:
Yes, prices have increased in some places due to high demand and supply shortages, but not to the extreme many posts suggest. Many pharmacies offer deals or subscription plans. You can also discuss switching to Wegovy, which may be more affordable depending on your country. Check our Trusted Suppliers list for regulated options.

Fiction:
Weight loss medication should be used in conjunction with amending your eating habits, improving your movement levels and adjusting your relationship with food. When you master this, you will be able to successfully maintain your weight loss when you stop taking the medication.

Fact:
Hair loss is not a direct effect of the drug. It usually happens because of telogen effluvium — when your body is under stress from rapid weight loss, calorie restriction, or nutrient shifts. Hair shedding is often temporary and improves as your body adapts. Adequate protein, vitamins, and overall nutrition can help reduce the impact.

Fiction:
Like any weight loss method, some lean mass can be lost. But GLP-1s don’t target muscle. With resistance training and good protein intake, you can maintain strength while losing fat.

Fiction:
Extracting liquid from GLP-1 pens is unsafe. You won’t know the true dose, the drug can become contaminated, and dosing this way is not supported. The only safe dose is the one prescribed..

Fact:
For some people. Fatigue is reported, usually from eating less, dehydration, or nutrient gaps. It’s often temporary, but persistent tiredness should be discussed with your prescribing doctor.

Fact:
Sulphur-smelling burps are a commonly reported side effect of GLP-1 and dual-agonist weight-loss medications such as Mounjaro (tirzepatide) and Wegovy (semaglutide). These drugs slow stomach emptying, meaning food stays in the stomach longer and can ferment, producing sulphur-containing gas. Eating smaller meals, reducing fatty foods, and avoiding fizzy drinks can help reduce this side effect.

Fact:
But it’s usually the weight loss, not the drug itself. Rapid weight loss increases gallstone risk, whether from diet, surgery, or medication. Staying hydrated and avoiding extreme calorie cuts may help..

Fact:
Sometimes. Women do report cycle changes. These are linked to weight loss and hormonal shifts, not the drug directly. If irregular bleeding continues, see a clinician.

Fiction:
Constipation is common but not universal. It happens because digestion slows and food volume drops. For many, more water, fibre, and light exercise solve it.

Fiction: Some suppliers will enable you to switch to them if you have proof of your starting weight and copies of your prescriptions from your previous supplier. This is another reason why keeping track of you progress is important. Firstly it keeps you motivated and secondly it is important if you need to speak to another medical professional for any reason.

Fiction: These medications were originally developed for diabetes, but versions such as Wegovy (semaglutide) and Zepbound/Mounjaro (tirzepatide) are now approved specifically for medical weight loss. They are prescribed for people with obesity or overweight with health risks—not only for those with diabetes.

Fiction: Most people experience some weight regain after stopping GLP-1 medications because appetite hormones return to normal. Long-term success requires ongoing lifestyle changes, nutrition support, and physical activity, even after discontinuing medication.

Fact: GLP-1 and dual-agonist medications slow gastric emptying, which can cause nausea, fullness, reflux, and occasional vomiting—especially during dose increases. Eating smaller meals, reducing fatty or greasy foods, and increasing water intake can significantly reduce this side effect.

Fact: Some people experience increased alcohol sensitivity or feel intoxicated more quickly while on GLP-1 medications because the drugs slow digestion and may affect how alcohol is absorbed. Drinking slowly, eating beforehand, and limiting intake can help you avoid unwanted effects.

Weight-loss medications like Mounjaro, Wegovy and Ozempic do not “stop working,” but weight loss naturally slows over time as the body adapts and calorie needs decrease. Plateaus are common with any weight-loss method. Adjusting nutrition, increasing protein intake, staying active, and following a structured medical weight-management plan can help restart progress

Fact:
Multiple large analyses and clinical studies show that when people stop taking GLP-1 and dual-agonist weight-loss medications such as Wegovy (semaglutide) and Mounjaro (tirzepatide), much of the lost weight often returns over time. A major review published in The BMJ found people regained weight at roughly 0.4 kg (nearly 1 lb) per month after stopping treatment, with many returning to their pre-treatment weight within around 1.5–1.7 years. (Reuters)
Systematic analyses also show that people typically regain more than half of the weight lost within about a year of discontinuing GLP-1 therapy, indicating that sustained lifestyle support and long-term management are key to lasting results.

Submit Your Own Question
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